[PUBLICATION] Microbubbles for Acoustically Mediated Drug Delivery to the Inner Ear

New Review Article Out !

This comprehensive review explores how microbubble-assisted ultrasound can overcome the physiological barriers of the inner ear and unlock new strategies for non-invasive, targeted delivery of drugs, proteins, and genes for hearing disorders. This work is the result of a close and long-standing collaboration between iBraiN, Inserm, Université de Tours, and the CHRU de Tours, perfectly illustrating the strength of integrated basic, translational, and clinical research in the field of otology and drug delivery.

Congratulations to the full author team for this collective effort: Charlotte Jeanneau, Fabrice Micaletti, Damien Fouan, Valérie Schubnel, Cédric Chauvierre, John J. Galvin III, Jean-Michel Escoffre, and David Bakhos. Special spotlight on Charlotte Jeanneau, first and corresponding author, who led the writing of this review with great scientific rigor and clarity. This work was carried out under the supervision of Jean-Michel Escoffre and David Bakhos, whose complementary expertise in ultrasound-mediated drug delivery and clinical ENT research strongly shaped the translational vision of the article. A great example of interdisciplinary mentorship in action !
 
We also gratefully acknowledge the support of our institutional and public funding bodies, whose commitment makes this type of collaborative research possible.

Interested in sonoporation, microbubbles, ultrasound-mediated delivery, or the future of inner ear therapies? We hope this review will be a valuable resource.

Feel free to read, share, and discuss !

#DrugDelivery #Ultrasound #Microbubbles #Sonoporation #InnerEar #HearingLoss #ENT