Socio-economics

 
socio-economic
iBraiN actively develops and maintains collaborations with industry. Any significant new findings discovered by iBraiN's scientists are thoroughly reviewed for patentability, prospective diagnostic and therapeutic applications, and industrial exploitation.

iBraiN is working in close collaboration with Inserm Transfert. This structure oversees and supports the patenting procedures to ensure sustainability of iBraiN patenting endeavors. Inserm Transfer follows our research activities to determine which goods and technologies could be developed and for which market in order to spark industrial interest. It also supports technical operations by designing pertinent proofs of concept and/or prototypes. Additionally, Inserm Transfert also supports the creation of start-ups.

The iBraiN Management Committee will take dedicated actions to ensure the successful creation of start-ups with the support of Inserm Transfert.

Since its creation, one company started at iBraiN, RhéaWave. Currently, iBraiN's researchers are named inventors or co-inventors on more than 10 applications for patents or their extensions. 13 patent families have been filed, and about 20 agreements (with KeyObs, Inviscan, Solstice Pharmaceuticals, Curium Pharma, Sanofi,...) are finalized annually. 

Within the framework of CIFRE (Convention Industrielle de Formation par la Recherche)  program, iBraiN also supports multiple PhD candidates (i.e. 1 CIFRE PhD grant/year on average) during their training.The CIFRE program provides companies such as Siemens, Carestream, Vermon, with financial assistance to recruit a PhD student whose research work, supervised by iBraiN, will lead to the PhD defense. It constitutes a lever for initiating and strengthening public-private cooperation in R&D and promoting the employment of doctors. It contributes to the innovation process of companies and their competitiveness.

New generations of MBs for BBBO

Solstice Pharmaceuticals

Industry-Academia Partnership - We collaborate with Solstice Pharmaceuticals to develop a new generation of microbubbles for blood–brain barrier opening and targeted delivery of therapeutic agents to treat neuropsychiatric, neurodegenerative, and neuro-oncological disorders.



 

Methods for Treating ASD

Chronic sodium bromide  & ASD
 
Patent - Chronic sodium bromide treatment alleviates autistic-like behaviors in multiple genetic mouse models of autism, likely through restoration of excitation–inhibition balance and positive allosteric modulation of mGlu4 receptors, highlighting its therapeutic potential for ASD - More information

Development of xD spectroscopic imaging for absolute quantification

Siemens Healthineers SAS
 
CIFRE PhD Thesis - This PhD project, conducted in partnership with Siemens Healthineers SAS, aims to develop a universal on-board device for routine clinical acquisition of absolute in vivo xD MR spectroscopy, with a particular focus on central nervous system pathologies.

Preclinical Models for ALS Therapy

Preclinical Models for ALS Therapy
 
Industry-Academia Partnership - Amyotrophic lateral sclerosis is a progressive and fatal neurodegenerative disease with no effective treatment, and this KeyObs partnership project aims to target pathogenic protein aggregates using intracellular antibody fragments to slow disease progression in ALS models and potentially other neurodegenerative disorders.