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Imaging & brain
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- [DISTINCTION] Ayache Bouakaz, « Distinguished Lecturer Award - 2023 »September 11, 2023 - October 2, 2023Ayache Bouakaz, DR Inserm, est le lauréat du programme « Distinguished Lecturer Award - 2023 » de la société savante internationale IEEE Ultrasonics, Ferroelectrics and Frequency Control Society (IEEE UFFC).
- [PRESSE] Le gaz hilarant pour soigner la dépression ? Des chercheurs tourangeaux prouvent un lien.September 11, 2023 - October 2, 2023Entretien avec Thomas Desmidt sur FranceBleu sur ces travaux sur l'intérêt du gaz hilarant dans la dépression.
- [PUBLICATION] Changes in cerebral connectivity and brain tissue pulsations with the antidepressant response to an equimolar mixture of oxygen and nitrous oxide: an MRI and ultrasound studyAugust 30, 2023 - September 25, 2023Une publication dans Molecular Psychiatry sur les mécanismes cérébraux de l'effet antidépresseur du Protoxyde d'azote, en IRMf et Ultrasons avec Thomas Desmidt, en collaboration avec Helmet T. Karim (Université de Pittsburg, USA).
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Who are we?
The Imaging and Brain Unit (iBrain, Inserm Unit 1253) is a multidisciplinary unit integrating research in Psychiatry, studies in cellular/molecular neuroscience and investigations aimed at developing new technologies for diagnosis and treatment of psychiatric disorders (focusing on methodologies relying on radiopharmaceuticals and ultrasound). It gathers experts in acoustics, chemistry, genetics, philosophy, psychiatry, linguistics, medical imaging, mathematics, neuroscience, philosophy, physics and radiochemistry.
Its main objective is to develop personalized therapies for psychiatric disorders, in particular autism and treatment-resistant depression, based on specific biomarkers predicting the efficacy of a given treatment.
The specific objectives of the unit are:
- to improve the comprehension of psychiatric and neurologic disorders by refining diagnosis and treatment
- to develop new imaging technologies and methodologies for the exploration of brain pathologies
- to develop innovative therapies for the treatment of cerebral pathologies
Neuro‐functional Psychiatry
We are studying the neurophysiological mechanisms involved in two psychiatric diseases: Autism and Depression. In the Autism project, we analyze neurophysiological signals and identify bioclinical signatures of autism. In the Depression project, we are looking for specific markers predicting the response / nonresponse to antidepressants and we are developing new innovative therapies.
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Neurogenomics and Neuronal Physiopathology
We seek to identify and study clinical, genetic, molecular, and pathophysiological markers in Intellectual Disabilities and Amyotrophic Lateral Sclerosis, specifically targeting glutamatergic neurons and their neuronal connections.
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Imaging, Biomarkers and Therapy
We develop and validate imaging technologies (Ultrasound, PET, MRI) to understand the neurophysiological mechanisms of psychiatric diseases. We develop new therapeutic strategies based on the use of ultrasound (ultrasound neurostimulation, sonoporation).
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Get in Touch
UMR 1253 Imagerie & Cerveau Faculté de Médecine 10 Bd Tonnellé Bât. Thérèse Planiol 37032 Tours Cedex 1 Secrétariat de l'unité Tel : + 33 (0)2 47 36 63 51 Email : u1253@univ-tours.fr |