Actualité

[PUBLICATION] Are single-donor red blood cell transfusions still relevant for preterm infants?

  • Recherche,
  • Santé-Sciences-Technologie,
  • Santé-social,
Date(s)

le 18 mai 2020

Published in J Perinatol

Collaborative research project led by Dr. Géraldine Favrais

Are single-donor red blood cell transfusions still relevant for preterm infants?

Abstract

Objective - To explore the worth of a single-donor program for preterm infants through the recipient profile and the impact on donor exposure, red blood cell (RBC) pack waste, storage duration, and transfusion performance.

Study design - Patients and transfusion characteristics were collected for 3 years (2015-2017) in preterm infants according to single-donor program prescription in a unit not practicing placental transfusion or erythropoietin supplementation.

Results - Among 1048 eligible preterm infants, 161 met the inclusion criteria, and 51 received single-donor packs. Our single-donor program induced a donor number reduction (34% less than the transfusion number) and an extension of storage duration (median: 9 versus 7 days, p < 0.0001) without altering the transfusion performance. However, 41% of small packs were not used.

Conclusion - A single-donor program partially reduced donor exposure but led to drastic RBC pack waste. Optimization of transfusion alternatives may increase this phenomenon, calling into question the rationale of this practice.

Keywords

#blood #preterminfants

Contact :
Dr. Géraldine Favrais :